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Kaiser Permanente Study: Opioid dose variability may be a risk factor for opioid overdose

Source Kaiser Permanente
Published Date 4/19/2019
Patients prescribed opioid pain medications whose doses varied over time were 3 times more likely to experience an overdose than patients prescribed stable opioid doses, according to an observational study from Kaiser Permanente published today in JAMA Network Open. The study also showed that patients who discontinued long-term opioid therapy for 3 or more months had half the risk of opioid overdose. ...
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